5 Future directions
5.1.9 Triggers for blood component transfusion
Question 9 (prognostic)
In patients undergoing surgery, at what INR (or PT/APTT) for FFP, fibrinogen level for cryoprecipitate and platelet count for platelets concentrates should patients be transfused to avoid risks of significant adverse events?
APTT, activated partial thromboplastin time; FFP, fresh frozen plasma; INR, international normalised ratio; PT, prothrombin time
There was insufficient evidence to define a threshold platelet count, fibrinogen level or INR (or PT/APTT) that is associated with significant adverse events in patients undergoing surgery. Well-designed studies are needed to address these evidence gaps.