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Index » Appendix I: International context » Transfusion Transmitted Injuries Surveillance System

Transfusion Transmitted Injuries Surveillance System

The Transfusion Transmitted Injuries Surveillance System (TTISS) has been monitoring adverse reactions related to the transfusion of blood components in Canada since 2001. From 2006 to 2012:

  • around 1.5 million transfusions of blood components were given in Canada each year
  • around 80% of these transfusions were monitored by the TTISS network
  • a total of 3,957 cases of transfusion-related adverse reactions were reported to the TTISS
  • 41 transfusion-related deaths were reported and only one was definitely caused by transfusion
  • other reports were either probably (n=12) or possibly (n=28) related to transfusion
  • the leading causes of death were TRALI and TACO which accounted for 71% of the cases.[66]
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