Conditions - Role in Therapy Index

The following index lists the same medical conditions as in the Alphabetical Index above, but by therapeutic role as they appear in Chapters 5 through to 8 of the full Criteria as follows:

Chapter 5Established therapeutic role
Chapter 6Emerging therapeutic role
Chapter 7Use in exceptional circumstance only
Chapter 8Use of IVIg is not supported

The above colour coding has been applied throughout the remainder of the QRG to identify relevant role in therapy conditions for which IVIg has an established therapeutic role

Conditions for which IVIg has an established therapeutic role
Acquired hypogammaglobulinaemia secondary to haematological malignancies
Chronic inflammatory demyelinating polyneuropathy
Guillain–Barré syndrome
Idiopathic (autoimmune) thrombocytopenia purpura (ITP) - Adult
Inflammatory myopathies
Kawasaki disease
Lambert–Eaton myasthenic syndrome
Multifocal motor neuropathy
Myasthenia gravis
Neonatal haemochromatosis
Primary immunodeficiency diseases
Stiff person syndrome
Conditions for which IVIg has an emerging therapeutic role
Acute disseminated encephalomyelitis
ANCA-positive systemic necrotising vasculitis
Autoimmune haemolytic anaemia
Bullous pemphigoid
Cicatricial pemphigoid
Evans syndrome - autoimmune haemolytic anaemia with immune thrombocytopenia
Foeto-maternal/neonatal alloimmune thrombocytopenia
Haemophagocytic syndrome
Idiopathic (autoimmune) thrombocytopenia purpura – Children 15 years and younger
IgM paraproteinaemic neuropathy
Kidney transplantation
Multiple sclerosis
Opsoclonus-Myoclonus ataxia
Pemphigus foliaceus
Pemphigus vulgaris
Post-transfusion purpura
Secondary hypogammaglobulinaemia (including iatrogenic immunodeficiency)
Specific antibody deficiency (including IgG subclasses)
Toxic epidermal necrolysis/Stevens–Johnson syndrome
Toxic shock syndrome
Conditions for which IVIg use is in exceptional circumstances only
Acute leukaemia in children
Autoimmune congenital heart block
Autoimmune neutropenia
Autoimmune uveitis
Catastrophic antiphospholipid syndrome
Coagulation factor inhibitors
Devic disease
Diabetic amyotrophy
Epidermolysis bullosa acquisita
Graves ophthalmopathy
Haemolytic disease of the newborn
Haemolytic transfusion reaction
Hashimoto encephalopathy
HIV in children
Limbic encephalitis - nonparaneoplastic
Limbic encephalitis - paraneoplastic
Myocarditis in children
Paediatric autoimmune neuropsychiatric disorder associated with streptococcal infections
Paraneoplastic cerebellar degeneration
Paraneoplastic subacute sensory neuropathy
Potassium channel antibody-associated encephalopathy
Pure red cell aplasia
Pure white cell aplasia
Pyoderma gangrenosum
Rasmussen syndrome
Sjogren’s syndrome
Solid organ transplantation (other than kidney)
Susac syndrome
Systemic capillary leak syndrome
Conditions for which IVIg use is not supported – not funded under the national Blood Arrangements
Acute optic neuritisHenoch–Schonlein purpura
Acute rheumatic feverHIV/AIDS — adult
AdrenoleukodystrophyIdiopathic dilated cardiomyopathy
Amegakaryocytic thrombocytopeniaLinear IgA disease
Antiphospholipid syndrome (non-obstetric)Lupus cerebritis
Aplastic anaemia/pancytopeniaLupus nephritis
AsthmaMotor neuron disease/amyotrophic lateral sclerosis
Atopic dermatitis/eczema — adultMyalgic encephalomyelitis
Autologous haemopoietic stem cell transplantationNephrotic syndrome
Behçet’s diseaseObsessive compulsive disorders
Cardiac surgery with bypass — prophylaxisPolyneuropathy of critical illness
Congestive cardiac failureRecurrent foetal loss (with or without antiphospholipid syndrome)
Crohn’s diseaseRheumatoid arthritis
Diamond Blackfan syndromeSepsis
Female infertilitySickle cell disease
Glomerulonephritis — IgA nephritisSystemic lupus erythematosus
Haemolytic uraemic syndromeUlcerative colitis