Patient Blood Management Guidelines: Module 1

Critical Bleeding Massive Transfusion

| Appendix |

Appendix F - Product information

Table F.1 Blood component product information and dosage – Australia

Component Content and characteristics Volume per baga Typical adult dose (~ 70 kg) Number of bags to provide typical dose
FFP
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Plasma recovered from a whole blood donation or apheresis collection

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Contains all coagulation factors

250–334 mL 10–15 mL/kg 3–4
Platelets: pooled
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A pool of platelets derived from the buffy coat of four whole blood donations

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Leucodepleted

>160 mL 1 bag 1
Platelets: apheresis
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A suspension of platelets prepared from a single apheresis donor

bullet
Leucodepleted

100–400 mL 1 bag 1
Cryo-precipitate
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Prepared from a single donated whole blood unit

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Contains an average of
> 0.35 g/bag

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Contains high levels of fibrinogen, factor VIII, von Willebrand factor, factor XIII, fibronectin

30–40 mL 3–4 g
fibrinogen
8–10
Cryo-precipitate: apheresis
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Prepared from FFP btained from a plasmapheresis donor

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Contains an average of
> 0.8 g/bag

60 mL (± 10%) 3–4 g
fibrinogen
4–5

FFP, fresh frozen plasma
a Actual volume indicated on label

Table F.2 Blood component product information and dosage – New Zealand

Component Content and characteristics Volume per baga Typical adult dose (~ 70 kg) Number of bags to provide typical dose
FFP
bullet
Plasma recovered from a whole blood donation or apheresis collection

bullet
Contains all coagulation factors

bullet
Leucodepleted

180–300 mL 10–15 mL/kg 3–4
Platelet pooled
bullet
A pool of platelets derived
from the buffy coat of four
whole blood donations

bullet
Leucodepleted

200–350 mL NA 1
Platelet apheresis
bullet
A suspension of platelets
prepared from a single
apheresis donor

bullet
Leucodepleted

180–400 mL NA 1
Cryo-precipitate
bullet
Prepared from FFPobtained from a plasmapheresis donor with a fibrinogen level > 2.4 g/L
bullet
Contains an average of 1.4 g/bag

bullet
Contains high levels of factor VIII, von Willebrand factor, factor XIII, fibronectin.

bullet
Leucodepleted
80–120 mL 3–4 g 2-3

FFP, fresh frozen plasma; NA, not applicable
a Actual volume indicated on label