This chapter provides clinical guidance in the form of recommendations (based on evidence) and practice points (based on CRG consensus). The guidance is organised around the eight questions that formed the basis of the systematic review. Full details of the findings of the systematic review are given in the accompanying technical report. 2,3 This chapter also provides guidance on adapting the MTP template (Appendix G) to suit the local patient population and healthâcare resources.
Patient Blood Management Guidelines: Module 1
Critical Bleeding Massive Transfusion
| Clinical practice guidance based on evidence or consensus |
4 Clinical practice guidance based on evidence or consensus
- 4.1Effect of physiological parameters on outcomes
- 4.2Effect of dose, timing and ratio of component therapy on outcomes
- 4.3Effect of anaemia on outcomes
- 4.4Effect of red cell transfusion on outcomes
- 4.5Effect of non-transfusion interventions to increase haemoglobin concentration
- 4.6Effect of recombinant activated factor VII on outcomes
- 4.7Effect of blood components on outcomes
- 4.8Triggers for blood component transfusion
- 4.9Effect of tranexamic acid
- 4.10 Development of a massive transfusion protocol
- 4.10.1 Local adaptation
- 4.10.2 Activation and cessation