Patient Blood Management Guidelines: Module 1

Critical Bleeding Massive Transfusion

| Future directions |

5.1 Evidence gaps and areas of future research

5.1.5 Effect of non-transfusion interventions to increase haemoglobin concentration

Question 5 (interventional)

In patients with critical bleeding requiring massive transfusion, what is the effect of non-transfusion interventions to increase haemoglobin concentration on morbidity, mortality and the need for RBC blood transfusion?

RBC, red blood cell

It is unlikely that non-transfusion interventions (e.g. haematinics and ESAs) to increase haemoglobin concentration will be able to be assessed for their effect on morbidity, mortality and the need for RBC transfusion in critically bleeding patients requiring massive transfusion.