Patient Blood Management Guidelines: Module 2

Perioperative

5 Future directions

5.1.7 Effect of recombinant activated factor VII on outcomes

Question 7 (interventional)

In patients undergoing surgery, what is the effect of rFVIIa (prophylaxis or treatment) on morbidity, mortality and transfusion rate?

rFVIIa, recombinant activated factor VII

Well-designed studies are needed to determine the impact of prophylactic or therapeutic use of rFVIIa on morbidity and mortality (including thrombosis) in surgical patients.