Appendix E - Blood component product information

Table E.1 Blood component product information and dosage – Australia

COMPONENT	CONTENT AND CHARACTERISTICS	VOLUME PER BAGa	TYPICAL ADULT DOSE (~ 70 KG)	NUMBER OF BAGS TO PROVIDE TYPICAL DOSE
FFP	Plasma recovered from a whole blood donation or apheresis collection Contains all coagulation factors	250–334 mL	10–15 mL/kg	3–4
Platelets: pooled	A pool of platelets derived from the buffy coat of four whole blood donations Leucodepleted	>160 mL	1 bag	1
Platelets: apheresis	A suspension of platelets prepared from a single apheresis donor Leucodepleted	100–400 mL	1 bag	1
Cryoprecipitate	Prepared from a single donated whole blood unit Contains an average of >0.35 g/bag Contains high levels of fibrinogen, factor VIII, von Willebrand factor, factor XIII, fibronectin	30–40 mL	3–4 g fibrinogen	8–10
Cryoprecipitate: apheresis	Prepared from FFP obtained from a plasmapheresis donor Contains an average of >0.8 g/bag	60 mL (± 10%)	3–4 g fibrinogen	4–5

FFP, fresh frozen plasma

a Actual volume indicated on label

Table E.2 Blood component product information and dosage - New Zealand

COMPONENT	CONTENT AND CHARACTERISTICS	VOLUME PER BAGa	TYPICAL ADULT DOSE (~ 70 KG)	NUMBER OF BAGS TO PROVIDE TYPICAL DOSE
FFP	Plasma recovered from a whole blood donation or apheresis collection Contains all coagulation factors Leucodepleted	180–300 mL	10–15 mL/kg	3–4
Platelets: pooled	A pool of platelets derived from the buffy coat of four whole blood donations Leucodepleted	200–350 mL	NA	1
Platelets: apheresis	A suspension of platelets prepared from a single apheresis donor Leucodepleted	180–400 mL	NA	1
Cryoprecipitate	Prepared from FFP obtained from a plasmapheresis donor with a fibrinogen level >2.4 g/L Contains an average of 1.4 g/bag Contains high levels of factor VIII, von Willebrand factor, factor XIII, fibronectin Leucodepleted	80–120 mL	3–4 g	2–3

FFP, fresh frozen plasma; NA, not applicable

a Actual volume indicated on label

Patient Blood Management Guidelines: Module 2