3.3 Effect of erythropoiesis- stimulating agents and iron

3.3.4 Elderly patients

Evidence Statements for Community-dwelling elderly
Evidence Statements –
community-dwelling elderly
Evidence Consistency Clinical impact Generalisability Applicability
ES3.30 In community-dwelling elderly patients with anaemia who are ambulatory, the effect of ESAs on mortality is uncertain. NA NA
ES3.31 In community-dwelling elderly patients with anaemia who are ambulatory, the effect of ESAs on thromboembolic events is uncertain. NA NA
ES3.32 In community-dwelling elderly patients with anaemia who are ambulatory, the effect of ESAs on functional or performance status is uncertain. NA X

ES, evidence statement; ESA, erythropoiesis-stimulating agent

=B; =C; X=D; NA,not applicable (see Table 2.1)

Erythropoiesis-stimulating agents – elderly patients

A single fair-quality RCT (Level II) of anaemic elderly patients receiving ESAs did not identify an effect on mortality or the incidence of thromboembolic complications.122 ESA treatment was associated with functional improvement.