There are important differences between children and adults, including blood volume, ability to tolerate blood loss, and age-appropriate haemoglobin and haematocrit levels.17
For practical purposes, massive transfusion in children may be defined as transfusion of > 40 mL blood/kg. A module dedicated to paediatrics (including neonates) will be available in Phase III of the patient blood management guidelines.
In children, ‘massive transfusion’ may be defined as a transfusion of more than 40 mL blood/kg.
(The normal blood volume of a child is approximately 80 mL/kg.)