3.8 Effect of blood components on outcomes
Question 8 (Interventional) GNQ5
In patients undergoing surgery, what is the effect of FFP, cryoprecipitate, fibrinogen concentrate, and/or platelet transfusion on patient outcomes?
FFP, fresh frozen plasma
3.8.1 Effect of fresh frozen plasma
One systematic review of the effect of FFP on patient outcomes in a perioperative population was identified. The study included six Level II studies (poor quality, due to small numbers and lack of allocation concealment).257 Overall, there was no evidence that the prophylactic use of FFP affected perioperative blood loss in cardiac surgery. In critically ill surgical patients, the administration of FFP may be associated with an increased risk of infection.258