Question 3 (aetiological)
In patients with critical bleeding requiring massive transfusion, is anaemia an independent risk factor for adverse outcomes?
Anaemia has been defined by the World Health Organization as a haemoglobin level < 130 g/L in males and < 120 g/L in females. In critically ill patients in intensive care, anaemia is commonly present, and a number of studies have assessed the association of anaemia with adverse outcomes. However, no studies were identified that assessed the association between anaemia and adverse outcomes in patients with critical bleeding requiring massive transfusion. It is unlikely that the effects of anaemia will be able to be independently assessed in this group of patients.
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Practice points
PP3 | In patients with critical bleeding requiring massive transfusion, haemoglobin concentration should be interpreted in the context of haemodynamic status, organ perfusion and tissue oxygenation. |
PP, practice point |